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Farmaceutiske mellemprodukter

Cardiovascular Intermediates

No. Produkter CAS NO. APPLICATION Vis mere
1 (R)-3-(Boc-amino)piperidin 309956-78-3 Linagliptin
2 Valsartan methylester 137863-17-3 Valsartan
3 Sitagliptin base 486460-32-6 Sitagliptin phosphate monohydrate
4 BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID 486460-00-8 Sitagliptin phosphate monohydrate
5 (1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy] phenyl] methyl]phenyl]-D-Glucitol 915095-99-7 Empagliflozin
6 (R)-3-(Boc-Amino)piperidine 309956-78-3 Linagliptin
7 8-Bromo-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione 853029-57-9 Linagliptin
8 2-Nitrobenzaldehyde 552-89-6 Nifedipine
9 2-[(2'-Cyano-Biphenyl-4-Ylmethyl)-Amino]-3- Methyl- Butyric Acid Methyl Ester 482577-59-3 Valsartan
10 Valsartan methyl ester 137863-17-3 Valsartan
11 Rosuvastatin R1 289042-12-2 Rosuvastatin calcium
12 Atorvastatin L1 125971-95-1 Atorvastatin calcium
13 D-(+)-Methyl-alpha-(2-thienylethamino) (2-chlorophenyl)acetate hydrochloride 141109-19-5 Clopidogrel
14 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]- 5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2 (4h)-one 150322-38-6 Prasugrel
15 Cyclopropyl 2-fluorobenzyl ketone 150322-73-9 Prasugrel
16 5,6,7,7a-tetrahydrothieno(3,2-c)pyridine-2(4h)-one hydrochloride 115473-15-9 Prasugrel
17 2-bromo-2-(2-fluorophenyl)-1- cyclopropylethanone 204205-33-4 Prasugrel
18 4-[4-[(5S)-5-(Aminomethyl)-2-oxo-1,3-oxazolidin[1]3-yl]phenyl]morpholin-3-one hydrochloride 898543-06-1 Rivaroxaban
19 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c] pyridine-3-carboxylic acid ethyl ester 503614-91-3 Apixaban

Anti-cancer Intermediates

No. Produkter CAS NO. APPLICATION Vis mere
1 Eldecalcitol Intermediate A 200636-54-0 Eldecalcitol
2 Eldecalcitol Mellemprodukter CD 144848-24-8 Eldecalcitol
3 Eldecalcitol mellemprodukt 200636-42-6 Eldecalcitol
4 4-chlor-3-(trifluormethyl)phenylisocyanat 327-78-6 Sorafenib
5 N-methyl-4-chlorpyridin-2-carboxamid 220000-87-3 Sorafenib
6 Terephthalsyre monomethylester 1679-64-7 Bexaroten
7 1,2,3,4-tetrahydro-1,1,4,4,6-pentamethyl-naphthalen 6683-48-3 Bexaroten
8 Methyl4-[(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoat 153559-45-6 Bexaroten
9 Benzoesyre, 4-[1-hydroxy-1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethyl] 852524-20-0 Bexaroten
10 Methyl-4-(chlorcarbonyl)benzoat 7377-26-6 Bexaroten
11 (4s,5r)-3-tert-butoxycarbony-2-(4-anisyl)-4- phenyl-5- oxazolidine carboxylic acid 196404-55-4 Docetaxel
12 7,10-o-ditroc docetaxel 114915-14-9 Docetaxel
13 Methyl(2r,3s)-n-tert-butoxycarbonyl-3-phenylisoserinat 124605-42-1 Docetaxel
14 5-fluor-2-oxindol 56341-41-4 Sunitinib
15 N-(2-(diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrol-3-carboxamid 356068-86-5 Sunitinib
16 N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidinamin 152460-10-1 Imatinib
17 4-[(4-methylpiperazin-1-yl)methyl]benzoesyredihydrochlorid 106261-49-8 Imatinib
18 Ethyl-4,5-bis(2-methoxyethoxy)-2-aminobenzoat 179688-27-8 Erlotinib
19 Ethyl-4,5-bis(2-methoxyethoxy)-2-nitrobenzoat 179688-26-7 Erlotinib
20 Ethyl-3,4-bis(2-methoxyethoxy)benzoat 183322-16-9 Erlotinib
21 Ethyl-3,4-dihydroxybenzoat 3943-89-3 Erlotinib
22 6,7-bis-(2-methoxyethoxy)-4(3h)-quinazolinon e 179688-29-0 Erlotinib
23 2-(methylsulfonyl)ethylamin-HCl 104458-24-4 Lapatinib
24 3-chlor-4-(3-fluorbenzyloxy)anilin 202197-26-0 Lapatinib
25 6-iodoquinazolin-4-ol 16064-08-7 Lapatinib
26 N-[3-chlor-4-(3-fluorbenzyloxy)phenyl]-6-i odoquinazolin-4-amin 231278-20-9 Lapatinib
27 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamidmonomethansulfonat 388082-78-8 Lapatinib
28 2-amino-5-iod-benzoesyre 5326-47-6 Lapatinib
29 4-chlor-6-iod-quinazolin 98556-31-1 Lapatinib
30 2-chlor-1-(3-fluor-benzyloxy)-4-nitro-benzen 443882-99-3 Lapatinib
31 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline 641571-11-1 Nolotinib
32 3-[(aminoiminomethyl)amino]-4-methylbenzoesyreethylestermononitrat 641569-96-2 Nolotinib
33 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoesyre 641569-94-0 Nolotinib
34 2,3,5-tri-o-benzyl-d-arabinofuranose-1-(4-nit robenzoat) 52522-49-3 Fludarabin phosphat
35 (R)-2,3-o-isopropyliden-glyceraldehyd 15186-48-8 Gemcitabin
36 2-deoxy-2,2-difluor-3,5-o-dibenzoylribosemesylat 122111-11-9 Gemcitabin
37 2-deoxy-2,2-difluoro-d-ribofuranose-3,5-dib enzoate 153012-08-9 Gemcitabine
38 2-deoxy-2’,2’-difluoro-3’5’-bis-o-benzoyleytidi ne monohydrochloride 134790-39-9 Gemcitabine
39 2-deoxy-2,2-difluor-D-erythro-pentofuranos-1-ulose-3,5-dibenzoat 122111-01-7 Gemcitabin
40 3,5-di-o-benzoyl-2-deoxy-2,2-difluor-1-o-methan-sulfonyl-d-ribofuranose 134877-43-3 Gemcitabin
41 Ethylbrom-difluoracetat 667-27-6 Gemcitabin
42 Methan-sulfonylchlorid 124-63-0 Gemcitabin
43 N-acetyl-n,o-bis-(trimethylsilyl)-cytosin N/A Gemcitabin
44 1,2,3-3-o-acetyl-5-deoxy-d-ribofuranose 62211-93-2 Capecitabin
45 2',3'-di-o-acetyl-5'-deoxy-5-fluorocytidin 161599-46-8 Capecitabin
46 5'-deoxy-5-fluor-n-[(pentyloxy)carbonyl]cytidin 2',3'-diacetat 162204-20-8 Capecitabin
47 4-(1-piperidino)piperidine; 1,4'-bipiperidine 4897-50-1 Irinotecan
48 1,4'-bipiperidin]-1'-carbonylchlorid HCI 143254-82-4 Irinotecan
49 7-ethyl-10-(chlorcarbonyloxy)camp til cin N/A Irinotecan
50 7-ethyl-10-hydroxycamptothecin 86639-52-3 Irinotecan
51 7-ethylcamptothecin 78287-27-1 Irinotecan
52 Camptothecin 7689-03-4 Irinotecan
53 N-(8-amino-6-fluor-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamid 182182-31-6 Exatecan
54 (S)-4-ethyl-4-hydroxy-7,8-dihydro-lh-pyrano[3,4-f]indolizin-3,6,10(4h)-trion 110351-94-5 Exatecan
55 1 h-1,2,4-triazol 288-88-0 Letrozol
56 4-(lh-1,2,4-triazol-1-ylmethyl)-benzonitrin 112809-25-3 Letrozol
57 4-(brommethyl)-benzonitril 17201-43-3 Letrozol
58 4-fluor-benzonitril 1194-02-1 Letrozol
59 2-brom-ethansulfonsyre 26978-65-4 Kødagtig
60 Thiourinstof 62-56-6 Kødagtig
61 (2r,3s)-3-phenylisoserin-hydrochlorid 132201-32-2 Paclitaxe
62 (2r,3s)-3-phenylisoserinmethyleste 131968-74-6 Paclitaxe
63 2,4-diamino-6-hydroxypyrimidin 56-06-4 Pemetrexed
64 4-[2-(2-amino-4,7-dihydro-4-oxo-lh-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoesyre 137281-39-1 Pemetrexed
65 Diethyl-l-glutamathydrochlorid 1118-89-4 Pemetrexed
66 1,2-dipalmitoyl-sn-glycerol 30334-71-5 Mifamurtide
67 1,2-dipalmitoyl-sn-glycero-3-phosphoethan-olamin 923-61-5 Mifamurtide
68 3-(4-chlorbutyl)-lH-indol-5-carbonitril 143612-79-7 Vilazodone
69 2-benzofurancarboxamider, 5-(1-piperazinyl)- 183288-46-2 Vilazodone
70 5-(1-piperazinyl)-2-benzofurancarboxylsyreethylesterhydrochlorid 765935-67-9 Vilazodone
71 Ethyl-5-aminobenzofuran-2-carboxylat 174775-48-5 Vilazodone
72 3-nitro-4-((tetrahydro-2H-pyran-4-yl)methylamino)benzensulfonamid 1228779-96-1 Venetoclax (ABT-199)
73 2-[(1H-pyrrolo[2,3-B]pyridin-5-yl)oxy]-4-[4-[[2-(4-chlorphenyl)-4,4-dimethylring Hex-1-enyl] methyl]piperazin-1-yl]benzoesyre 1235865-77-6 Venetoclax (ABT-199)
74 5-[4-((3-chlor-4-((3-fluorbenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-furaldehyd 231278-84-5 Lapatinib
75 Abiraterone 154229-19-3 Abiraterone acetate

Antipsychotics Intermediates

No. Produkter CAS NO. APPLICATION Vis mere
1 4-Methoxyphenylacetone 122-84-9 Dimefline
2 (3aR,7aR)-4'-(1,2-benzisothiazol-3-yl)octahydrospiro[2H-isoindol-2,1'-piperaziniuM]-methansulfonat 186204-37-5 Lurasidon
3 1,1-cyclohexandieddikesyre monoamid 99189-60-3 Gabapentin
4 (R)-(-)-3-Carbamoymethyl-5-methylhexansyre 181289-33-8 Pregabalin
5 1-naphthalenethanamin, 7-methoxy-hydrochlorid 139525-77-2 Agomelatin
6 7-methoxy-1-naphthaleneddikesyre 6836-22-2 Agomelatin
7 7-methoxy-1-naphthaleneddikesyreethylester 6836-21-1 Agomelatin
8 7-methoxy-1-naphthylacetonitril 138113-08-3 Agomelatin
9 8-chlor-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-on 50892-62-1 Clozapin
10 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride 138564-60-0 Olanzapine
11 2-(2-nitroanilino)-5-methylthiophene-3-carb onitrile 138564-59-7 Olanzapine
12 2-amino-3-cyano-5-methylthiophen 138564-58-6 Olanzapin
13 O-chlornitro-benzen 88-73-3 Olanzapin
14 3-[(1S)-1-(Dimethylaminoethyl)]phenol 139306-10-8 Rivastigmine
15 L(+)-Tartaric acid 87-69-4 Rivastigmine
16 Ethylmethyl-carbaminchlorid 42252-34-6 Rivastigmin tartrat
17 3-(1-(dimethylamino)ethyl]phenol 105601-04-5 Rivastigmin tartrat
18 pentamethylene bis[1-(3,4-dimethoxybenzyl)-3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], dioxalate 64228-78-0 Cisatracurium besylate
19 Tetrahydropapaverin hydrochlorid 6429-4-5 Cisatracurium besylat
20 R-Tetrahydropapaverin N-acetyl-L-leucinat 141109-12-8 Cisatracurium besylat
21 1,5-pentandiol diacrylat 36840-85-4 Cisatracurium besylat
22 3-aminopyrrolidin-dihydrochlorid 103831-11-4 Levetiracetam
23 (R)-(+)-1-Boc-3-aminopyrrolidin 147081-49-0 Levetiracetam
24 (3R)-(-)-3-aminopyrrolidin-dihydrochlorid 116183-81-4 Levetiracetam
25 Dapoxetin base 119356-77-3 Dapoxetin
26 1-Fluoronaphthalene 321-38-0 Duloxetine
27 4-fluorbenzoylacetonitril 4640-67-9 Blonanserin
28 Cyclooctan-1-one 502-49-8 Blonanserin
29 4-(4-fluorobenzyl)-5,6,7,8,9,10-hexacyclooctyl pyridine-2(1-H)-one N/A Blonanserin
30 2-chlor-4-(4-fluorbenzyl)-5,6,7,8,9,10-hexacyclooctylpyridin N/A Blonanserin
31 N-Methylparoxetine 110429-36-2 Paroxetine hydrochloride
32 (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine 105812-81-5 Paroxetine hydrochloride
33 3,4-dihydro-7-hydroxy-2(1H)-quinolinon 22246-18-0 Aripiprazol
34 1-(2,3-dichlorphenyl)piperazin-hydrochlorid 119532-26-2 Aripiprazol
35 (1R,1'R)-2,2'-(3,11-Dioxo-4,10-dioxatridecamethylen)-bis-(1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquindlin) -dioxalat 96687-52-4 Cisatracurium besylat
36 2-(2-carboxyethyl)-1-[(3,4-dimethoxyphenyl)methyl]-,1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinoliniumbenzensulfonat 1075727-06-8 Cisatracurium besylat
37 cis-Paroxetin hydrochlorid 105813-04-5 Paroxetin hydrochlorid

Antipyretic, antibacterial intermedaites

No. Produkter CAS NO. APPLICATION Vis mere
1 Salicylsyre 69-72-7 Aspirin
2 4-Hydroxy-D-(-)-2-phenylglycin 22818-40-2 Amoxicillin
3 6-Aminopenicillansyre 551-16-6 Amoxicillin
4 4-aminophenol 123-30-8 Acetaminophen
5 4-chlornitrobenzen 100-00-5 Acetaminophen
6 Azathramycin 76801-85-9 Azithromycin
7 Quinolinsyre 89-00-9 Levofloxacin hydrochlorid
8 Ethyl (S)-9,10-difluor-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazin-6-carboxylat 106939-34-8 Levofloxacin hydrochlorid
9 1-(2,6-dichlorphenyl)indolin-2-on 15362-40-0 Diclofenac natrium
10 N-(2',6'-DIMETHYLPHENYL)-PIPERIDIN-2- CARBOXYL-AMID 15883-20-2 Diclofenac natrium
11 3-amino-4-pyrazolcarboxamid-hemisulfat 27511-79-1 Allopurinol
12 Remdesivir impurity 21 1911578-98-7 Remdesivir
13 REDESIVIR N-2 1191237-80-5 Remdesivir
14 Guanosine 118-00-3 Valaciclovir

Others Intermediates and Solvents

No. Produkter CAS NO. APPLICATION Vis mere
1 Montelukast Dicyclohexylamin Salt 577953-88-9 Montelukast
2 2-(2-HYDROXYPHENYL)-4H-1,3-BENZOXAZIN-4-ON 1218-69-5 Deferasirox
3 (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-methylpentansyre 1012341-50-2 AHU-377 (heMicalciuM salt)
4 4-chlor-1-methylpiperidin-hydrochlorid 5382-23-0 Loratadin
5 Acetonitril 75-05-8 Insekticid
6 Myresyre 64-18-6 De reducerer
7 Dimethylsulfoxid 67-68-5 Reaktionsreagens
8 2,4-dichlorbenzaldehyd 874-42-0 bakteriedræbende
9 2,6-dichlorbenzaldehyd 83-38-5 Insekticid
10 Dimethylformamid 68-12-2 Insekticid
11 p-nitrobenzoesyre 62-23-7 Mellemliggende
12 Magnesium 7439-95-4 De reducerer
13 1-propanthiol 107-03-9 Insekticid
14 Meglumine 6284-40-8 Cosolvent
15 4-Hydrazinobenzoesyre 619-67-0 Deferasirox
16 2-[2-(2,2,2-trifluorethoxy)phenoxy]ethylmethansulfonat 160969-03-9 Silodosin
17 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indol-7-carbonitril (2R,3R)-2,3-dihydroxybutandioat 239463-85-5 Silodosin
18 Methyldopa 41372-08-1 API hypotensor
19 1,3-Dimethyladamantane 702-79-4 Memantine hydrochloride intermediate
20 1,4-Dibromobutane 110-52-1 Intermediates of organic synthesis
21 4-chloranilin 106-47-8 Farvestof mellemliggende
22 p-nitrobenzoesyre 62-23-7 Mellemliggende
23 p-aminobenzamid 2835-68-9 Farvestof mellemliggende
24 Kaliumhydroxid 1310-58-3 Mellemliggende
25 Chlortrimethylsilan 75-77-4 Mellemliggende
26 N-(trimethylsilyl)imidazol 18156-74-6 Mellemliggende
27 4-tert-octylphenol 140-66-9 Mellemliggende
28 Cytidin 5'-monophosphat 63-37-6 Mellemliggende
29 alfa-methylkanelaldehyd 101-39-3 Mellemliggende
30 4-tert-butylcatechol 98-29-3 Mellemliggende
31 Formamid 75-12-7 Opløsningsmiddel/mellemprodukt
32 Malonsyre 141-82-2 Mellemliggende
33 Methylsalicylat 119-36-8 API / opløsningsmiddel / mellemliggende
34 1,1'-Carbonyldiimidazol 530-62-1 Mellemliggende
35 1-Methylpiperazin 109-01-3 Mellemliggende
36 3-Cyanopyridin 100-54-9 Mellemliggende
37 Piperazine 110-85-0 Intermediate
38 Bis(2-ethylhexyl) phthalate 117-81-7 Solvent
39 Tetrahydrofurfurylalkohol 97-99-4 Opløsningsmiddel
40 Tetrahydrofuran 109-99-9 Opløsningsmiddel
41 Dimethylsulfon 67-71-0 Opløsningsmiddel